Well depends how expensive (and old) your PSU is in the first place, if it's an expensive one then maybe if you cleaned it out a bit, it could stop making the noise, depening on the location of your PC, the amount of dust the PC can gather is crazy, (As I found out when I opened my sisters desktop recently, over an inch of duch at the base of the case.) But if it's not expensive or you are worried about messing up the internal if you open things up get a replacement PSU. you can get a different brand, but should make sure it's the same size and atleast the same power (though better if more) than your current PC.
Quote:
Originally Posted by runeazn
buy a Antec or a Corsair 
they have great reputation.
i myself use a 1150W Coolermaster UCP
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Dude what kind of monster set-up do you have? My PC only has a 500w PSU and it only uses 400w max, its also a Coolmaster. I have learnt that it makes sense to by a decent quality PSU over the years. Usually the first thing I replace if I buy a off the shelf PC, with a generic PSU.